Interleukin 7 receptor engagement stimulates tyrosine phosphorylation, inositol phospholipid turnover, proliferation, and selective differentiation to the CD4 lineage by human fetal thymocytes.

The purposes of this study were to elucidate the effects of recombinant human interleukin 7 (rhIL-7) on proliferation as well as differentiation of human fetal thymocytes and to analyze the biochemical nature of the IL-7 receptor-linked transmembrane signal. In the absence of costimulants, rhIL-7 st...

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Detalhes bibliográficos
Main Authors: Uckun, F M, Tuel-Ahlgren, L, Obuz, V, Smith, R, Dibirdik, I, Hanson, M, Langlie, M C, Ledbetter, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC52075/
https://ncbi.nlm.nih.gov/pubmed/2068112
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