Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death.

Very little is known regarding the effects of ionizing radiation on cytoplasmic signal transduction pathways. Here, we show that ionizing radiation induces enhanced tyrosine phosphorylation of multiple substrates in human B-lymphocyte precursors. This response to ionizing radiation was also observed...

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Detalhes bibliográficos
Main Authors: Uckun, F M, Tuel-Ahlgren, L, Song, C W, Waddick, K, Myers, D E, Kirihara, J, Ledbetter, J A, Schieven, G L
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50053/
https://ncbi.nlm.nih.gov/pubmed/1409597
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