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Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with low survival rates and limited therapeutic options. Thus elucidation of signaling pathways involved in PDAC pathogenesis is essential for identifying novel potential therapeutic gene targets. Here, we used a systems approach to elu...

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書目詳細資料
發表在:Am J Physiol Gastrointest Liver Physiol
Main Authors: Vorvis, Christina, Hatziapostolou, Maria, Mahurkar-Joshi, Swapna, Koutsioumpa, Marina, Williams, Jennifer, Donahue, Timothy R., Poultsides, George A., Eibl, Guido, Iliopoulos, Dimitrios
格式: Artigo
語言:Inglês
出版: American Physiological Society 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005285/
https://ncbi.nlm.nih.gov/pubmed/27151939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00035.2016
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