Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with low survival rates and limited therapeutic options. Thus elucidation of signaling pathways involved in PDAC pathogenesis is essential for identifying novel potential therapeutic gene targets. Here, we used a systems approach to elu...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Gastrointest Liver Physiol
Asıl Yazarlar: Vorvis, Christina, Hatziapostolou, Maria, Mahurkar-Joshi, Swapna, Koutsioumpa, Marina, Williams, Jennifer, Donahue, Timothy R., Poultsides, George A., Eibl, Guido, Iliopoulos, Dimitrios
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2016
Konular:
Call for Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005285/
https://ncbi.nlm.nih.gov/pubmed/27151939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00035.2016
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