Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with low survival rates and limited therapeutic options. Thus elucidation of signaling pathways involved in PDAC pathogenesis is essential for identifying novel potential therapeutic gene targets. Here, we used a systems approach to elu...

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Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: Vorvis, Christina, Hatziapostolou, Maria, Mahurkar-Joshi, Swapna, Koutsioumpa, Marina, Williams, Jennifer, Donahue, Timothy R., Poultsides, George A., Eibl, Guido, Iliopoulos, Dimitrios
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
Matèries:
Call for Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005285/
https://ncbi.nlm.nih.gov/pubmed/27151939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00035.2016
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