Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens. MicroRNAs have been involved in the pathogenesis of different types of cancers, including liver can...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Principais autores: Drakaki, Alexandra, Hatziapostolou, Maria, Polytarchou, Christos, Vorvis, Christina, Poultsides, George A., Souglakos, John, Georgoulias, Vassilis, Iliopoulos, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512159/
https://ncbi.nlm.nih.gov/pubmed/26206264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1562-9
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