Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens. MicroRNAs have been involved in the pathogenesis of different types of cancers, including liver can...

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發表在:BMC Cancer
Main Authors: Drakaki, Alexandra, Hatziapostolou, Maria, Polytarchou, Christos, Vorvis, Christina, Poultsides, George A., Souglakos, John, Georgoulias, Vassilis, Iliopoulos, Dimitrios
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512159/
https://ncbi.nlm.nih.gov/pubmed/26206264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1562-9
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