Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens. MicroRNAs have been involved in the pathogenesis of different types of cancers, including liver can...

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Publicado en:BMC Cancer
Autores principales: Drakaki, Alexandra, Hatziapostolou, Maria, Polytarchou, Christos, Vorvis, Christina, Poultsides, George A., Souglakos, John, Georgoulias, Vassilis, Iliopoulos, Dimitrios
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512159/
https://ncbi.nlm.nih.gov/pubmed/26206264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1562-9
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