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Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy

Mutations in the ferritin light chain (FTL) gene cause the neurodegenerative disease neuroferritinopathy or hereditary ferritinopathy (HF). HF is characterized by a severe movement disorder and by the presence of nuclear and cytoplasmic iron-containing ferritin inclusion bodies (IBs) in glia and neu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garringer, Holly J., Irimia, Jose M., Li, Wei, Goodwin, Charles B., Richine, Briana, Acton, Anthony, Chan, Rebecca J., Peacock, Munro, Muhoberac, Barry B., Ghetti, Bernardino, Vidal, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004847/
https://ncbi.nlm.nih.gov/pubmed/27574973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161341
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