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Cryo-EM structures and functional characterization of homo- and heteropolymers of human ferritin variants
The role of abnormal brain iron metabolism in neurodegenerative diseases is still insufficiently understood. Here, we investigate the molecular basis of the neurodegenerative disease hereditary ferritinopathy (HF), in which dysregulation of brain iron homeostasis is the primary cause of neurodegener...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7692541/ https://ncbi.nlm.nih.gov/pubmed/33244127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77717-4 |
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