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ACCUMULATION OF OXIDATIVE DNA DAMAGE IN BRAIN MITOCHONDRIA IN MOUSE MODEL OF HEREDITARY FERRITINOPATHY
Tissue iron content is strictly regulated to concomitantly satisfy specialized metabolic requirements and avoid toxicity. Ferritin, a multi-subunit iron storage protein, is central to maintenance of iron homeostasis in the brain. Mutations in the ferritin light chain (FTL)-encoding gene underlie the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914088/ https://ncbi.nlm.nih.gov/pubmed/20478358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.05.025 |
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