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ACCUMULATION OF OXIDATIVELY GENERATED DNA DAMAGE IN THE BRAIN: A MECHANISM OF NEUROTOXICITY

Unrepaired or erroneously repaired DNA lesions drive genomic instability and contribute to cellular and organ decline. Since delayed neuropathologies are common in survivors of smoke inhalation injuries, we asked whether the integrity of brain DNA might be compromised by acute exposure to combustion...

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Detalhes bibliográficos
Main Authors: Chen, Liuji, Lee, Heung M, Greeley, George H, Englander, Ella W
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049091/
https://ncbi.nlm.nih.gov/pubmed/17210451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.11.009
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