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Regulation of CpG methylation by Dnmt and Tet in pluripotent stem cells

Vertebrate genomes are highly methylated at cytosine residues in CpG sequences. CpG methylation plays an important role in epigenetic gene silencing and genome stability. Compared with other epigenetic modifications, CpG methylation is thought to be relatively stable; however, it is sometimes affect...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: HORII, Takuro, HATADA, Izuho
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004787/
https://ncbi.nlm.nih.gov/pubmed/27151232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2016-046
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