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Differential landscape of non-CpG methylation in embryonic stem cells and neurons caused by DNMT3s

Methylated non-CpGs (mCpH; H means A, C, and T) have emerged as key epigenetic marks in mammalian embryonic stem cells (ESCs) and neurons, regulating cell type-specific functions. In these two cell types, mCpHs show distinct motifs and correlations to transcription that could be a key in understandi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Jong-Hun, Park, Sung-Joon, Nakai, Kenta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595995/
https://ncbi.nlm.nih.gov/pubmed/28900200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11800-1
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