Evolution of a FLT3-TKD mutated subclone at meningeal relapse in acute promyelocytic leukemia

Here, we report the case of an acute promyelocytic leukemia (APL) patient who—although negative for FLT3 mutations at diagnosis—developed isolated FLT3 tyrosine kinase II domain (FLT3-TKD)-positive meningeal relapse, which, in retrospect, could be traced back to a minute bone marrow subclone present...

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書目詳細資料
發表在:Cold Spring Harb Mol Case Stud
Main Authors: Bochtler, Tilmann, Fröhling, Stefan, Weichert, Wilko, Endris, Volker, Thiede, Christian, Hutter, Barbara, Hundemer, Michael, Ho, Anthony D., Krämer, Alwin
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2016
主題:
Research Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002926/
https://ncbi.nlm.nih.gov/pubmed/27626069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a001123
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