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BK channel regulation by phosphodiesterase type 1: a novel signaling pathway controlling human detrusor smooth muscle function

Large-conductance Ca(2+)-activated K(+) (BK) channels are critical regulators of detrusor smooth muscle (DSM) function. We aimed to investigate phosphodiesterase type 1 (PDE1) interactions with BK channels in human DSM to determine the mechanism by which PDE1 regulates human urinary bladder physiolo...

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Опубликовано в: :Am J Physiol Renal Physiol
Главные авторы: Xin, Wenkuan, Li, Ning, Fernandes, Vitor S., Chen, Biao, Rovner, Eric S., Petkov, Georgi V.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002058/
https://ncbi.nlm.nih.gov/pubmed/26911851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00452.2015
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