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Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation

cTnI(P82S) (cTnI(P83S) in rodents) resides at the I-T arm of cardiac troponin I (cTnI) and was initially identified as a disease-causing mutation of hypertrophic cardiomyopathy (HCM). However, later studies suggested this may not be true. We recently reported that introduction of an HCM-associated m...

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Pubblicato in:J Phys Chem B
Autori principali: Cheng, Yuanhua, Lindert, Steffen, Oxenford, Lucas, Tu, An-yue, McCulloch, Andrew D., Regnier, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001945/
https://ncbi.nlm.nih.gov/pubmed/27150586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b01859
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