Učitavanje...

Effects of HCM cTnI Mutation R145G on Troponin Structure and Modulation by PKA Phosphorylation Elucidated by Molecular Dynamics Simulations

Cardiac troponin (cTn) is a key molecule in the regulation of human cardiac muscle contraction. The N-terminal cardiac-specific peptide of the inhibitory subunit of troponin, cTnI (cTnI(1-39)), is a target for phosphorylation by protein kinase A (PKA) during β-adrenergic stimulation. We recently pre...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Lindert, Steffen, Cheng, Yuanhua, Kekenes-Huskey, Peter, Regnier, Michael, McCammon, J. Andrew
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302190/
https://ncbi.nlm.nih.gov/pubmed/25606687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3461
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!