Effects of HCM cTnI Mutation R145G on Troponin Structure and Modulation by PKA Phosphorylation Elucidated by Molecular Dynamics Simulations

Lignende værker

• Long-Timescale Molecular Dynamics Simulations Elucidate the Dynamics and Kinetics of Exposure of the Hydrophobic Patch in Troponin C
  af: Lindert, Steffen, et al.
  Udgivet: (2012)
• PKA Phosphorylation of Cardiac Troponin I Modulates Activation and Relaxation Kinetics of Ventricular Myofibrils
  af: Rao, Vijay, et al.
  Udgivet: (2014)
• Computational Studies of the Effect of the S23D/S24D Troponin I Mutation on Cardiac Troponin Structural Dynamics
  af: Cheng, Yuanhua, et al.
  Udgivet: (2014)
• Molecular Basis of Calcium-Sensitizing and Desensitizing Mutations of the Human Cardiac Troponin C Regulatory Domain: A Multi-Scale Simulation Study
  af: Kekenes-Huskey, Peter Michael, et al.
  Udgivet: (2012)
• Troponin I Mutations R146G and R21C Alter Cardiac Troponin Function, Contractile Properties, and Modulation by Protein Kinase A (PKA)-mediated Phosphorylation
  af: Cheng, Yuanhua, et al.
  Udgivet: (2015)