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Rational engineering of the Neurospora VS ribozyme to allow substrate recognition via different kissing-loop interactions
The Neurospora VS ribozyme is a catalytic RNA that has the unique ability to specifically recognize and cleave a stem-loop substrate through formation of a highly stable kissing-loop interaction (KLI). In order to explore the engineering potential of the VS ribozyme to cleave alternate substrates, w...
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| 發表在: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001590/ https://ncbi.nlm.nih.gov/pubmed/27166370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw401 |
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