Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3.

Experiments using recombinant vaccinia viruses expressing rat proinsulin I coinfected into COS-7 cells with recombinant vaccinia virus expressing human furin, human PC2, mouse PC3 (subtilisin-related proprotein convertases 1-3, respectively), or yeast Kex2 indicate that in this system both Kex2 and...

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Main Authors: Smeekens, S P, Montag, A G, Thomas, G, Albiges-Rizo, C, Carroll, R, Benig, M, Phillips, L A, Martin, S, Ohagi, S, Gardner, P
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50013/
https://ncbi.nlm.nih.gov/pubmed/1528899
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