Escherichia coli MutY protein has both N-glycosylase and apurinic/apyrimidinic endonuclease activities on A.C and A.G mispairs.

In Escherichia coli the mutY (or micA)-dependent DNA mismatch repair pathway can convert A degrees G and A degrees C mismatches to C.G and G.C base pairs, respectively, through a short repair-tract mechanism. The MutY protein has been purified to near homogeneity from an E. coli overproducer strain....

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Tsai-Wu, J J, Liu, H F, Lu, A L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50004/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1382298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.18.8779
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