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Apurinic/apyrimidinic endonuclease 1 performs multiple roles in controlling the outcome of cancer cells toward radiation and chemotherapeutic agents

Many endogenous and exogenous sources produce reactive oxygen species such as superoxide radical anions and hydrogen peroxide that are converted to the highly reactive form, hydroxyl radical. It is this latter species that can damage several macromolecules in the cells, in particular, the DNA to pro...

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Detalhes bibliográficos
Principais autores: Dindial Ramotar, Alain Nepveu
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2018-01-01
Colecção:Journal of Radiation and Cancer Research
Assuntos:
Acesso em linha:http://www.journalrcr.org/article.asp?issn=0973-0168;year=2018;volume=9;issue=2;spage=67;epage=78;aulast=Ramotar
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