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Structural Architecture of Prothrombin in Solution Revealed by Single Molecule Spectroscopy

The coagulation factor prothrombin has a complex spatial organization of its modular assembly that comprises the N-terminal Gla domain, kringle-1, kringle-2, and the C-terminal protease domain connected by three intervening linkers. Here we use single molecule Förster resonance energy transfer to ac...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pozzi, Nicola, Bystranowska, Dominika, Zuo, Xiaobing, Di Cera, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000060/
https://ncbi.nlm.nih.gov/pubmed/27435675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738310
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