In Vitro and In Vivo Synergy of the Oxadiazole Class of Antibacterials with β-Lactams

The oxadiazole antibacterials target the bacterial cell wall and are bactericidal. We investigated the synergism of ND-421 with the commonly used β-lactams and non-β-lactam antibiotics by the checkerboard method and by time-kill assays. ND-421 synergizes well with β-lactam antibiotics, and it also e...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Janardhanan, Jeshina, Meisel, Jayda E., Ding, Derong, Schroeder, Valerie A., Wolter, William R., Mobashery, Shahriar, Chang, Mayland
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997879/
https://ncbi.nlm.nih.gov/pubmed/27401567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00787-16
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