Discovery of a Potent Picolinamide Antibacterial Active against Clostridioides difficile

A major challenge for chemotherapy of bacterial infections is perturbation of the intestinal microbiota. Clostridioides difficile is a Gram-positive bacterium of the gut that can thrive under this circumstance. Its production of dormant and antibiotic-impervious spores results in chronic disruption...

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Bibliografische gegevens
Gepubliceerd in:ACS Infect Dis
Hoofdauteurs: Speri, Enrico, Janardhanan, Jeshina, Masitas, Cesar, Schroeder, Valerie A., Lastochkin, Elena, Wolter, William R., Fisher, Jed F., Mobashery, Shahriar, Chang, Mayland
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716698/
https://ncbi.nlm.nih.gov/pubmed/32786277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00479
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