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Discovery of a Potent Picolinamide Antibacterial Active against Clostridioides difficile
A major challenge for chemotherapy of bacterial infections is perturbation of the intestinal microbiota. Clostridioides difficile is a Gram-positive bacterium of the gut that can thrive under this circumstance. Its production of dormant and antibiotic-impervious spores results in chronic disruption...
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| Publié dans: | ACS Infect Dis |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7716698/ https://ncbi.nlm.nih.gov/pubmed/32786277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00479 |
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