Depletion of γ-catenin by Histone Deacetylase Inhibition Confers Elimination of CML Stem Cells in Combination with Imatinib

Quiescent leukemia stem cells (LSCs) that are insensitive to BCR-ABL tyrosine kinase inhibitors confer resistance to imatinib in chronic myelogenous leukemia (CML). Identifying proteins to regulate survival and stemness of LSCs is urgently needed. Although histone deacetylase inhibitors (HDACis) can...

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Detaylı Bibliyografya
Yayımlandı:Theranostics
Asıl Yazarlar: Jin, Yanli, Yao, Yiwu, Chen, Li, Zhu, Xiaohui, Jin, Bei, Shen, Yingying, Li, Juan, Du, Xin, Lu, Yuhong, Jiang, Sheng, Pan, Jingxuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ivyspring International Publisher 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997248/
https://ncbi.nlm.nih.gov/pubmed/27570562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.16139
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