Amino Acids, Independent of Insulin, Attenuate Skeletal Muscle Autophagy in Neonatal Pigs during Endotoxemia

BACKGROUND: Sepsis induces loss of skeletal muscle mass by activating the ubiquitin proteasome (UPS) and autophagy systems. Although muscle protein synthesis in healthy neonatal piglets is responsive to amino acid (AA) stimulation, it is not known if amino acids (AA) can prevent the activation of mu...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Pediatr Res
Hlavní autoři: Hernandez-García, Adriana, Manjarín, Rodrigo, Suryawan, Agus, Nguyen, Hanh V., Davis, Teresa A., Orellana, Renán A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996682/
https://ncbi.nlm.nih.gov/pubmed/27064245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.83
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky