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Amino Acids, Independent of Insulin, Attenuate Skeletal Muscle Autophagy in Neonatal Pigs during Endotoxemia

BACKGROUND: Sepsis induces loss of skeletal muscle mass by activating the ubiquitin proteasome (UPS) and autophagy systems. Although muscle protein synthesis in healthy neonatal piglets is responsive to amino acid (AA) stimulation, it is not known if amino acids (AA) can prevent the activation of mu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pediatr Res
Egile Nagusiak: Hernandez-García, Adriana, Manjarín, Rodrigo, Suryawan, Agus, Nguyen, Hanh V., Davis, Teresa A., Orellana, Renán A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996682/
https://ncbi.nlm.nih.gov/pubmed/27064245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.83
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