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Insulin Signaling in Skeletal Muscle and Liver of Neonatal Pigs During Endotoxemia

Sepsis has been associated with tumor necrosis factor α (TNF-α) and nitric oxide (NO) overproduction, insulin resistance, and a profound suppression of muscle protein synthesis. However, lesser suppression of muscle protein synthesis in neonatal pigs occurs in response to endotoxin (LPS) when glucos...

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Main Authors: Orellana, Renán A., Suryawan, Agus, Kimball, Scot R., Wu, Guoyao, Nguyen, Hanh V., Jefferson, Leonard S., Davis, Teresa A.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774270/
https://ncbi.nlm.nih.gov/pubmed/18596577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e318183fd4c
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