Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably Expressed in HEK-293 Cells

The voltage dependent sodium channel Nav1.9, is expressed preferentially in peripheral sensory neurons and has been linked to human genetic pain disorders, which makes it target of interest for the development of new pain therapeutics. However, characterization of Nav1.9 pharmacology has been limite...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lin, Zhixin, Santos, Sonia, Padilla, Karen, Printzenhoff, David, Castle, Neil A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996523/
https://ncbi.nlm.nih.gov/pubmed/27556810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161450
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