Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases

AIM: Particle Replication in Nonwetting Templates (PRINT(®)) PLGA nanoparticles of docetaxel and acid-labile C2-dimethyl-Si-Docetaxel were evaluated with small molecule docetaxel as treatments for non-small-cell lung cancer brain metastases. MATERIALS & METHODS: Pharmacokinetics, survival, tumor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nanomedicine (Lond)
Prif Awduron: Sambade, Maria, Deal, Allison, Schorzman, Allison, Luft, J Christopher, Bowerman, Charles, Chu, Kevin, Karginova, Olga, Swearingen, Amanda Van, Zamboni, William, DeSimone, Joseph, Anders, Carey K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Future Medicine Ltd 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996152/
https://ncbi.nlm.nih.gov/pubmed/27456556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2016-0147
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