Nanoparticle Drug Loading as a Design Parameter to Improve Docetaxel Pharmacokinetics and Efficacy

Nanoparticle (NP) drug loading is one of the key defining characteristics of a NP formulation. However, the effect of NP drug loading on therapeutic efficacy and pharmacokinetics has not been thoroughly evaluated. Herein, we characterized the efficacy, toxicity and pharmacokinetic properties of NP d...

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Bibliografski detalji
Glavni autori: Chu, Kevin S., Schorzman, Allison N., Finniss, Mathew C., Bowerman, Charles J., Peng, Lei, Luft, J. Christopher, Madden, Andrew, Wang, Andrew Z., Zamboni, William C., DeSimone, Joseph M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807740/
https://ncbi.nlm.nih.gov/pubmed/23899444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.07.038
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