Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer

INTRODUCTION: Breast cancer brain metastases (BCBM) are a challenging consequence of advanced BC. Nanoparticle agents, including liposomes, have shown enhanced delivery to solid tumors and brain. We compared pharmacokinetics (PK) and efficacy of PEGylated liposomal doxorubicin (PLD) with non-liposom...

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書誌詳細
主要な著者: Anders, Carey K., Adamo, Barbara, Karginova, Olga, Deal, Allison M., Rawal, Sumit, Darr, David, Schorzman, Allison, Santos, Charlene, Bash, Ryan, Kafri, Tal, Carey, Lisa, Miller, C. Ryan, Perou, Charles M., Sharpless, Norman, Zamboni, William C.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641071/
https://ncbi.nlm.nih.gov/pubmed/23650496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061359
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