Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer

INTRODUCTION: Breast cancer brain metastases (BCBM) are a challenging consequence of advanced BC. Nanoparticle agents, including liposomes, have shown enhanced delivery to solid tumors and brain. We compared pharmacokinetics (PK) and efficacy of PEGylated liposomal doxorubicin (PLD) with non-liposom...

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Huvudupphovsmän: Anders, Carey K., Adamo, Barbara, Karginova, Olga, Deal, Allison M., Rawal, Sumit, Darr, David, Schorzman, Allison, Santos, Charlene, Bash, Ryan, Kafri, Tal, Carey, Lisa, Miller, C. Ryan, Perou, Charles M., Sharpless, Norman, Zamboni, William C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641071/
https://ncbi.nlm.nih.gov/pubmed/23650496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061359
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