Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson’s Disease

Mitochondrial dysfunction, oxidative stress and neuroinflammation have been implicated as key mediators contributing to the progressive degeneration of dopaminergic neurons in Parkinson’s disease (PD). Currently, we lack a pharmacological agent that can intervene in all key pathological mechanisms,...

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Veröffentlicht in:J Neuroimmune Pharmacol
Hauptverfasser: Ghosh, Anamitra, Langley, Monica R, Harischandra, Dilshan, Neal, Matthew L, Jin, Huajun, Anantharam, Vellareddy, Joseph, Joy, Brenza, Timothy, Narasimhan, Balaji, Kanthasamy, Arthi, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995106/
https://ncbi.nlm.nih.gov/pubmed/26838361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-016-9650-4
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