Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson’s Disease

Mitochondrial dysfunction, oxidative stress and neuroinflammation have been implicated as key mediators contributing to the progressive degeneration of dopaminergic neurons in Parkinson’s disease (PD). Currently, we lack a pharmacological agent that can intervene in all key pathological mechanisms,...

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Vydáno v:J Neuroimmune Pharmacol
Hlavní autoři: Ghosh, Anamitra, Langley, Monica R, Harischandra, Dilshan, Neal, Matthew L, Jin, Huajun, Anantharam, Vellareddy, Joseph, Joy, Brenza, Timothy, Narasimhan, Balaji, Kanthasamy, Arthi, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995106/
https://ncbi.nlm.nih.gov/pubmed/26838361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-016-9650-4
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