Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson’s Disease

Mitochondrial dysfunction, oxidative stress and neuroinflammation have been implicated as key mediators contributing to the progressive degeneration of dopaminergic neurons in Parkinson’s disease (PD). Currently, we lack a pharmacological agent that can intervene in all key pathological mechanisms,...

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Foilsithe in:J Neuroimmune Pharmacol
Main Authors: Ghosh, Anamitra, Langley, Monica R, Harischandra, Dilshan, Neal, Matthew L, Jin, Huajun, Anantharam, Vellareddy, Joseph, Joy, Brenza, Timothy, Narasimhan, Balaji, Kanthasamy, Arthi, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995106/
https://ncbi.nlm.nih.gov/pubmed/26838361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-016-9650-4
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