BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

Multiple myeloma (MM) evolves from a premalignant condition known as monoclonal gammopathy of undetermined significance (MGUS). However, the factors underlying the malignant transformation of plasmocytes in MM are not fully characterized. We report here that Eµ-directed expression of the antiapoptot...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Hamouda, Mohamed-Amine, Jacquel, Arnaud, Robert, Guillaume, Puissant, Alexandre, Richez, Valentine, Cassel, Romeo, Fenouille, Nina, Roulland, Sandrine, Gilleron, Jerome, Griessinger, Emmanuel, Dubois, Alix, Bailly-Maitre, Beatrice, Goncalves, Diogo, Mallavialle, Aude, Colosetti, Pascal, Marchetti, Sandrine, Amiot, Martine, Gomez-Bougie, Patricia, Rochet, Nathalie, Deckert, Marcel, Avet-Loiseau, Herve, Hofman, Paul, Karsenti, Jean-Michel, Jeandel, Pierre-Yves, Blin-Wakkach, Claudine, Nadel, Bertrand, Cluzeau, Thomas, Anderson, Kenneth C., Fuzibet, Jean-Gabriel, Auberger, Patrick, Luciano, Frederic
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995074/
https://ncbi.nlm.nih.gov/pubmed/27455953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150983
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