The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer

Increased APOBEC3B mRNA levels are associated with a hypermutator phenotype and poor prognosis in ER-positive breast cancer patients. In addition, a 29.5 kb deletion polymorphism of APOBEC3B, resulting in an APOBEC3A-B hybrid transcript, has been associated with an increased breast cancer risk and t...

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Veröffentlicht in:PLoS One
Hauptverfasser: Liu, Jingjing, Sieuwerts, Anieta M., Look, Maxime P., van der Vlugt-Daane, Michelle, Meijer-van Gelder, Marion E., Foekens, John A., Hollestelle, Antoinette, Martens, John W. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995039/
https://ncbi.nlm.nih.gov/pubmed/27552096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161731
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