Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers

Recent observations connected DNA cytosine deaminase APOBEC3B to the genetic evolution of breast cancer. We addressed whether APOBEC3B is associated with breast cancer clinical outcomes. APOBEC3B messenger RNA (mRNA) levels were related in 1,491 primary breast cancers to disease-free (DFS), metastas...

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Detalhes bibliográficos
Publicado no:Horm Cancer
Main Authors: Sieuwerts, Anieta M., Willis, Scooter, Burns, Michael B., Look, Maxime P., Gelder, Marion E. Meijer-Van, Schlicker, Andreas, Heideman, Marinus R., Jacobs, Heinz, Wessels, Lodewyk, Leyland-Jones, Brian, Gray, Kathryn P., Foekens, John A., Harris, Reuben S., Martens, John W. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228172/
https://ncbi.nlm.nih.gov/pubmed/25123150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-014-0196-8
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