Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers

Recent observations connected DNA cytosine deaminase APOBEC3B to the genetic evolution of breast cancer. We addressed whether APOBEC3B is associated with breast cancer clinical outcomes. APOBEC3B messenger RNA (mRNA) levels were related in 1,491 primary breast cancers to disease-free (DFS), metastas...

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Dettagli Bibliografici
Pubblicato in:Horm Cancer
Autori principali: Sieuwerts, Anieta M., Willis, Scooter, Burns, Michael B., Look, Maxime P., Gelder, Marion E. Meijer-Van, Schlicker, Andreas, Heideman, Marinus R., Jacobs, Heinz, Wessels, Lodewyk, Leyland-Jones, Brian, Gray, Kathryn P., Foekens, John A., Harris, Reuben S., Martens, John W. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2014
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228172/
https://ncbi.nlm.nih.gov/pubmed/25123150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-014-0196-8
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