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High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genes

INTRODUCTION: The TWIST homolog 1 (TWIST1) is a transcription factor that induces epithelial to mesenchymal transition (EMT), a key process in metastasis. The purpose of this study was to investigate whether TWIST1 expression predicts disease progression in a large breast cancer cohort with long-ter...

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Detalhes bibliográficos
Main Authors: Riaz, Muhammad, Sieuwerts, Anieta M, Look, Maxime P, Timmermans, Mieke A, Smid, Marcel, Foekens, John A, Martens, John WM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053101/
https://ncbi.nlm.nih.gov/pubmed/22967435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3317
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