Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis

Reduced mitochondrial DNA (mtDNA) content in breast cancer cell lines has been associated with transition towards a mesenchymal phenotype, but its clinical consequences concerning breast cancer dissemination remain unidentified. Here, we aimed to clarify the link between mtDNA content and a mesenchy...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Weerts, Marjolein J.A., Sieuwerts, Anieta M., Smid, Marcel, Look, Maxime P., Foekens, John A., Sleijfer, Stefan, Martens, John W.M.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045386/
https://ncbi.nlm.nih.gov/pubmed/27081694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8688
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