Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis

Reduced mitochondrial DNA (mtDNA) content in breast cancer cell lines has been associated with transition towards a mesenchymal phenotype, but its clinical consequences concerning breast cancer dissemination remain unidentified. Here, we aimed to clarify the link between mtDNA content and a mesenchy...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Weerts, Marjolein J.A., Sieuwerts, Anieta M., Smid, Marcel, Look, Maxime P., Foekens, John A., Sleijfer, Stefan, Martens, John W.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045386/
https://ncbi.nlm.nih.gov/pubmed/27081694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8688
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