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Methylated Cytosines Mutate to Transcription Factor Binding Sites that Drive Tetrapod Evolution
In mammals, the cytosine in CG dinucleotides is typically methylated producing 5-methylcytosine (5mC), a chemically less stable form of cytosine that can spontaneously deaminate to thymidine resulting in a T•G mismatched base pair. Unlike other eukaryotes that efficiently repair this mismatched base...
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| 出版年: | Genome Biol Evol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4994754/ https://ncbi.nlm.nih.gov/pubmed/26507798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv205 |
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