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Idiopathic pulmonary fibrosis fibroblasts become resistant to Fas ligand-dependent apoptosis via the alteration of decoy receptor 3
Idiopathic pulmonary fibrosis (IPF) is an irreversible lethal lung disease with an unknown aetiology. IPF patient’s lung fibroblasts express inappropriately high Akt activity, protecting them in response to an apoptosis-inducing type I collagen matrix. FasL, a ligand for Fas, is known to be increase...
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| Veröffentlicht in: | J Pathol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993669/ https://ncbi.nlm.nih.gov/pubmed/27218286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4749 |
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