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SUMO-interacting motifs (SIMs) in Polo-like kinase 1-interacting checkpoint helicase (PICH) ensure proper chromosome segregation during mitosis

Polo-like kinase 1 (Plk1)-interacting checkpoint helicase (PICH) localizes at the centromere and is critical for proper chromosome segregation during mitosis. However, the precise molecular mechanism of PICH's centromeric localization and function at the centromere is not yet fully understood....

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Sridharan, Vinidhra, Azuma, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993536/
https://ncbi.nlm.nih.gov/pubmed/27230136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1191713
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