SUMOylation Regulates Polo-like Kinase 1-interacting Checkpoint Helicase (PICH) during Mitosis

Mitotic SUMOylation has an essential role in faithful chromosome segregation in eukaryotes, although its molecular consequences are not yet fully understood. In Xenopus egg extract assays, we showed that poly(ADP-ribose) polymerase 1 (PARP1) is modified by SUMO2/3 at mitotic centromeres and that its...

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Publicat a:J Biol Chem
Autors principals: Sridharan, Vinidhra, Park, Hyewon, Ryu, Hyunju, Azuma, Yoshiaki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
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Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319000/
https://ncbi.nlm.nih.gov/pubmed/25564610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C114.601906
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