Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells

Rickettsia (R.) typhi is the causative agent of endemic typhus, an emerging febrile disease that is associated with complications such as pneumonia, encephalitis and liver dysfunction. To elucidate how innate immune mechanisms contribute to defense and pathology we here analyzed R. typhi infection o...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Papp, Stefanie, Moderzynski, Kristin, Rauch, Jessica, Heine, Liza, Kuehl, Svenja, Richardt, Ulricke, Mueller, Heidelinde, Fleischer, Bernhard, Osterloh, Anke
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993389/
https://ncbi.nlm.nih.gov/pubmed/27548618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004935
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