CD4(+) T Cells Are as Protective as CD8(+) T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity

Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia, hepatitis and meningoencephalitis, the latter being a regular outcome in T and B cell-deficient C57BL/6 RAG1(-/-) mice upon Rickettsia typhi infect...

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Gepubliceerd in:PLoS Negl Trop Dis
Hoofdauteurs: Moderzynski, Kristin, Papp, Stefanie, Rauch, Jessica, Heine, Liza, Kuehl, Svenja, Richardt, Ulricke, Fleischer, Bernhard, Osterloh, Anke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119731/
https://ncbi.nlm.nih.gov/pubmed/27875529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005089
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