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MDA‐5 activation by cytoplasmic double‐stranded RNA impairs endothelial function and aggravates atherosclerosis

Recent studies have highlighted the relevance of viral nucleic acid immunorecognition by pattern recognition receptors in atherogenesis. Melanoma differentiation associated gene 5 (MDA‐5) belongs to the intracellular retinoic acid inducible gene‐I like receptors and its activation promotes pro‐infla...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Asdonk, Tobias, Steinmetz, Martin, Krogmann, Alexander, Ströcker, Christine, Lahrmann, Catharina, Motz, Inga, Paul‐Krahe, Kathrin, Flender, Anna, Schmitz, Theresa, Barchet, Winfried, Hartmann, Gunther, Nickenig, Georg, Zimmer, Sebastian
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993381/
https://ncbi.nlm.nih.gov/pubmed/27130701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12864
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