MDA‐5 activation by cytoplasmic double‐stranded RNA impairs endothelial function and aggravates atherosclerosis

Recent studies have highlighted the relevance of viral nucleic acid immunorecognition by pattern recognition receptors in atherogenesis. Melanoma differentiation associated gene 5 (MDA‐5) belongs to the intracellular retinoic acid inducible gene‐I like receptors and its activation promotes pro‐infla...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Asdonk, Tobias, Steinmetz, Martin, Krogmann, Alexander, Ströcker, Christine, Lahrmann, Catharina, Motz, Inga, Paul‐Krahe, Kathrin, Flender, Anna, Schmitz, Theresa, Barchet, Winfried, Hartmann, Gunther, Nickenig, Georg, Zimmer, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993381/
https://ncbi.nlm.nih.gov/pubmed/27130701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12864
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