MDA‐5 activation by cytoplasmic double‐stranded RNA impairs endothelial function and aggravates atherosclerosis

Recent studies have highlighted the relevance of viral nucleic acid immunorecognition by pattern recognition receptors in atherogenesis. Melanoma differentiation associated gene 5 (MDA‐5) belongs to the intracellular retinoic acid inducible gene‐I like receptors and its activation promotes pro‐infla...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Asdonk, Tobias, Steinmetz, Martin, Krogmann, Alexander, Ströcker, Christine, Lahrmann, Catharina, Motz, Inga, Paul‐Krahe, Kathrin, Flender, Anna, Schmitz, Theresa, Barchet, Winfried, Hartmann, Gunther, Nickenig, Georg, Zimmer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993381/
https://ncbi.nlm.nih.gov/pubmed/27130701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12864
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