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Metabolic actions of the type 1 cholecystokinin receptor: its potential as a therapeutic target

Cholecystokinin regulates appetite and reduces food intake by activating the type 1 CCK receptor (CCK1R). Attempts to develop CCK1R agonists for obesity have yielded active agents that have not reached clinical practice. In this review we discuss why, along with new strategies to target CCK1R more e...

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Detalhes bibliográficos
Publicado no:Trends Endocrinol Metab
Main Authors: Miller, Laurence J., Desai, Aditya J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992613/
https://ncbi.nlm.nih.gov/pubmed/27156041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2016.04.002
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