Molecular mechanism of action of triazolobenzodiazepinone agonists of the type 1 cholecystokinin receptor. Possible cooperativity across the receptor homo-dimeric complex

Lignende værker

• Molecular Basis for Benzodiazepine Agonist Action at the Type 1 Cholecystokinin Receptor
  af: Harikumar, Kaleeckal G., et al.
  Udgivet: (2013)
• Development of a Highly Selective Allosteric Antagonist Radioligand for the Type 1 Cholecystokinin Receptor and Elucidation of Its Molecular Basis of Binding
  af: Dong, Maoqing, et al.
  Udgivet: (2015)
• Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor
  af: Dong, Maoqing, et al.
  Udgivet: (2016)
• Elimination of a cholecystokinin receptor agonist “trigger” in an effort to develop positive allosteric modulators without intrinsic agonist activity
  af: Desai, Aditya J., et al.
  Udgivet: (2015)
• Molecular Basis for Binding and Subtype Selectivity of 1,4-Benzodiazepine Antagonist Ligands of the Cholecystokinin Receptor
  af: Cawston, Erin E., et al.
  Udgivet: (2012)